{
  "_id": "6ac4c3eaf511ae58c09a105f",
  "Package": "wISAM",
  "Type": "Package",
  "Title": "Weighted Inbred Strain Association Mapping",
  "Version": "0.2.8",
  "Author": "Robert W. Cort <rcorty@gmail.com>",
  "Maintainer": "Robert W. Cort <rcorty@gmail.com>",
  "Description": "In the course of a genome-wide association study, the\nsituation often arises that some phenotypes are known with\ngreater precision than others. It could be that some\nindividuals are known to harbor more micro-environmental\nvariance than others. In the case of inbred strains of model\norganisms, it could be the case that more organisms were\nobserved from some strains than others, so the strains with\nmore organisms have better-estimated means. Package 'wISAM'\nhandles this situation by allowing for weighting of each\nobservation according to residual variance. Specifically, the\n'weight' parameter to the function conduct_scan() takes the\nprecision of each observation (one over the variance).",
  "License": "GPL-3",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "RoxygenNote": "6.0.1",
  "Repository": "https://rcorty.r-universe.dev",
  "Date/Publication": "2018-06-07 15:49:24 UTC",
  "RemoteUrl": "https://github.com/rcorty/wisam",
  "RemoteRef": "HEAD",
  "RemoteSha": "9d90e9d810aecbf626b3cf20e84f8efe85450abe",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-10-06 09:44:14 UTC",
    "User": "root"
  },
  "_user": "rcorty",
  "_type": "src",
  "_file": "wISAM_0.2.8.tar.gz",
  "_fileid": "https://r2.ropensci.org/1ff3ad258bc59844794bb39e252d90fd9fcb454b278d013198e955d57e76d70a",
  "_filesize": 226982,
  "_sha256": "1ff3ad258bc59844794bb39e252d90fd9fcb454b278d013198e955d57e76d70a",
  "_expires": "2027-01-14T09:48:24.000Z",
  "_created": "2026-10-06T09:44:14.000Z",
  "_published": "2026-10-06T09:48:26.145Z",
  "_jobs": [
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  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/rcorty/actions/runs/37444651849",
  "_status": "success",
  "_upstream": "https://github.com/rcorty/wisam",
  "_commit": {
    "id": "9d90e9d810aecbf626b3cf20e84f8efe85450abe",
    "author": "Robert Corty <rcorty@gmail.com>",
    "committer": "Robert Corty <rcorty@gmail.com>",
    "message": "got it on CRAN\n",
    "time": 1528386564
  },
  "_maintainer": {
    "name": "Robert W. Cort",
    "email": "rcorty@gmail.com",
    "login": "rcorty",
    "orcid": "0000-0002-6787-9051",
    "twitter": "@rwcorty",
    "description": "interested in immunology, especially auto-immunity",
    "uuid": 718555
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.0.0",
      "role": "Depends"
    },
    {
      "package": "methods",
      "role": "Imports"
    },
    {
      "package": "MASS",
      "role": "Imports"
    },
    {
      "package": "testthat",
      "role": "Suggests"
    }
  ],
  "_owner": "rcorty",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_topics": [
    "genetics",
    "gwas",
    "gwas-tools",
    "lmm",
    "mixed-models"
  ],
  "_stars": 0,
  "_contributors": [
    {
      "user": "rcorty",
      "count": 9,
      "uuid": 718555
    }
  ],
  "_userbio": {
    "uuid": 718555,
    "type": "user",
    "name": "Robert W. Corty",
    "followers": 23,
    "description": "interested in immunology, especially auto-immunity"
  },
  "_downloads": {
    "count": 227,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/wISAM"
  },
  "_devurl": "https://github.com/rcorty/wisam",
  "_searchresults": 13,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/manual.pdf",
    "extra/readme.html",
    "extra/readme.md",
    "extra/wISAM.html"
  ],
  "_homeurl": "https://github.com/rcorty/wisam",
  "_realowner": "rcorty",
  "_cranurl": true,
  "_releases": [
    {
      "version": "0.2.8",
      "date": "2018-06-04"
    }
  ],
  "_exports": [
    "check_eigen_decomposition",
    "GenomeScan"
  ],
  "_datasets": [
    {
      "name": "covariate_mat",
      "title": "Example covariate matrix",
      "object": "covariate_mat",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [],
      "rows": 200,
      "table": true,
      "tojson": true
    },
    {
      "name": "kinship_mat",
      "title": "Example kinship matrix",
      "object": "kinship_mat",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [],
      "rows": 200,
      "table": true,
      "tojson": true
    },
    {
      "name": "locus_list",
      "title": "Example locus list",
      "object": "locus_list",
      "class": [
        "list"
      ],
      "fields": [],
      "table": true,
      "tojson": true
    },
    {
      "name": "phenotype",
      "title": "Example phenotype",
      "object": "phenotype",
      "class": [
        "numeric"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "se_mean_per_strain",
      "title": "Example standard error of the mean per strain",
      "object": "se_mean_per_strain",
      "class": [
        "numeric"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "check_eigen_decomposition",
      "title": "check_eigen_decomposition",
      "topics": [
        "check_eigen_decomposition"
      ]
    },
    {
      "page": "covariate_mat",
      "title": "Example covariate matrix",
      "topics": [
        "covariate_mat"
      ]
    },
    {
      "page": "GenomeScan_calc_multiplier_eigen",
      "title": "calc_multiplier_eigen",
      "topics": [
        "GenomeScan_calc_multiplier_eigen"
      ]
    },
    {
      "page": "GenomeScan_conduct_scan",
      "title": "conduct_scan",
      "topics": [
        "GenomeScan_conduct_scan"
      ]
    },
    {
      "page": "GenomeScan_fit_locus",
      "title": "fit_locus",
      "topics": [
        "GenomeScan_fit_locus"
      ]
    },
    {
      "page": "GenomeScan_fit_locus_given_h2",
      "title": "fit_locus_given_h2",
      "topics": [
        "GenomeScan_fit_locus_given_h2"
      ]
    },
    {
      "page": "GenomeScan_initialize",
      "title": "initialize",
      "topics": [
        "GenomeScan_initialize"
      ]
    },
    {
      "page": "GenomeScan_prep_scan",
      "title": "prep_scan",
      "topics": [
        "GenomeScan_prep_scan"
      ]
    },
    {
      "page": "GenomeScan-class",
      "title": "GenomeScan",
      "topics": [
        "GenomeScan",
        "GenomeScan-class"
      ]
    },
    {
      "page": "kinship_mat",
      "title": "Example kinship matrix",
      "topics": [
        "kinship_mat"
      ]
    },
    {
      "page": "locus_list",
      "title": "Example locus list",
      "topics": [
        "locus_list"
      ]
    },
    {
      "page": "phenotype",
      "title": "Example phenotype",
      "topics": [
        "phenotype"
      ]
    },
    {
      "page": "se_mean_per_strain",
      "title": "Example standard error of the mean per strain",
      "topics": [
        "se_mean_per_strain"
      ]
    }
  ],
  "_readme": "https://github.com/rcorty/wisam/raw/HEAD/README.md",
  "_rundeps": [
    "MASS"
  ],
  "_score": 2.8129133566428557,
  "_indexed": true,
  "_nocasepkg": "wisam",
  "_universes": [
    "rcorty"
  ],
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